Homochiral Acyl Isocyanates as Diagnostic NMR Probes for the Enantiomeric Purity of Chiral Alcohols

Authors

Gregory H. P. Roos, Department of Chemistry, College of Science, Sultan Qaboos University, P.O. Box 36, Al Khod 123, Muscat, Sultanate of Oman.
Anthony R. Donovanb, Chemistry Department, Division of Science, Murdoch University, South Street, Murdoch, Australia 6150.

Abstract

The first reported acyl and sulfonylisocyanates were developed and tested in reactions with chiral alcohols to afford diastereomeric carbamates. NMR analysis of these investigates the chemical shift discrimination that would allow these activated isocyanates to be used as diagnostic probes of enantiomeric purity.

Recommended Citation

Roos, Gregory H. P. and Donovanb, Anthony R. (2000) Homochiral Acyl Isocyanates as Diagnostic NMR Probes for the Enantiomeric Purity of Chiral Alcohols, Sultan Qaboos University Journal For Science: Vol. 5: Iss. 1, 11-23.
DOI: https://doi.org/10.24200/squjs.vol5iss0pp11-23
Available at: https://squjs.squ.edu.om/squjs/vol5/iss1/9